The most common side effects of the drug include nausea, headache, dry mouth and sleepiness — but more serious side effects may occur. Like most antidepressants, Cymbalta (duloxetine) may trigger suicidal thoughts and behavior in children, adolescents and adults under the age of 24.
What are the worst side effects of Cymbalta?
Tell your doctor right away if any of these serious side effects occur: confusion, easy bruising/bleeding, decreased interest in sex, changes in sexual ability, muscle cramps/weakness, shaking (tremor), difficulty urinating, signs of liver problems (such as nausea that doesn’t go away, stomach/abdominal pain, vomiting,
What is the best time of day to take Cymbalta?
It is best to take Cymbalta (duloxetine) at the same time every day. Most people take it in the morning, but if you find that you feel drowsy after taking it in the morning, try taking it in the evening.
How long does Cymbalta side effects last?
How long do side effects last? Most common side effects of Cymbalta are temporary. Some will get better as the body adjusts to the drug or the underlying depression or anxiety improves. Other common side effects will improve about one or two days after the last dose is taken.
When should you not take Cymbalta?
You should not use this medicine if you have had an allergic reaction to duloxetine, or if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days. You should not use this medicine if you have uncontrolled narrow-angle glaucoma.
What are the dangers of taking Cymbalta?
What Are Possible Side Effects Of Duloxetine? Headache, nausea, diarrhea, dry mouth, decreased appetite, increased sweating, feeling nervous, restless, fatigued, sleepy or having trouble sleeping (insomnia). These will often improve over the first week or two as you continue to take the medication.
Does Cymbalta cause weight loss?
Conclusion: Duloxetine-treated patients experienced weight loss after short-term treatment, followed by modest weight gain on longer-term treatment. The size of the weight changes observed suggests that the antidepressant duloxetine has minimal effects on weight for the majority of patients.
Is Cymbalta an anti inflammatory?
The anti-inflammatory activity of duloxetine, a serotonin/norepinephrine reuptake inhibitor, prevents kainic acid-induced hippocampal neuronal death in mice. J Neurol Sci. 2015 Nov 15;358(1-2):390-7.
How do you know if Cymbalta is not working?
Signs that your antidepressant might not be working include:
- You feel more or the same amount of sadness, anxiety, or irritability after several weeks or months of taking the medication.
- You feel slightly better, but still feel that your depression is affecting your ability to function.
- You are having trouble sleeping.
Is 30 mg of Cymbalta effective?
Conclusions: Results from this open-label study in patients with MDD suggest that starting duloxetine treatment at 30 mg QD for 1 week, followed by escalation to 60 mg QD, might reduce the risk for treatment-emergent nausea in these patients while producing only a transitory impact on effectiveness compared with a
Does Cymbalta change your personality?
Results to date suggest that duloxetine can produce adaptive changes in behavioural and neural mechanisms that characterise low mood, consistent with growing evidence that antidepressants can modulate emotion recognition and social functioning in clinical depression.
Is it better to take Cymbalta in the morning or at night?
It is best to take duloxetine at the same time each day. Most people take it in the morning. If you find that you feel drowsy after taking it in the morning, try taking it in the evening.
Can you drink caffeine with Cymbalta?
If you drink a lot of coffee, cola drinks or other caffeine drinks when taking duloxetine, it can put you at a higher risk of getting serotonin syndrome. The symptoms are any combination of the following: high fever. agitation.
Is Cymbalta hard on the kidneys?
Cymbalta should not damage your kidney function with Stage 3 chronic kidney disease (CKD). Your prescribing physician should take this into consideration.
What drugs should not be taken with duloxetine?
Do not take duloxetine within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant.
Can I take Tylenol with Cymbalta?
No interactions were found between acetaminophen and Cymbalta. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Does your brain go back to normal after antidepressants?
The process of healing the brain takes quite a bit longer than recovery from the acute symptoms. In fact, our best estimates are that it takes 6 to 9 months after you are no longer symptomatically depressed for your brain to entirely recover cognitive function and resilience.
Does Cymbalta cause brain fog?
Short-Term Memory Loss and Brain Fog
A lack of short-term memory, difficulty in concentrating, and brain zaps are just some of the complaints experienced by people taking Cymbalta.
Can Cymbalta cause joint pain?
Check with your doctor right away if you have blistering, peeling, or loosening of the skin, chills, cough, diarrhea, itching, joint or muscle pain, red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, or unusual tiredness or weakness
Can Paxil cause hair loss?
Antidepressants and mood stabilizers
Some people who take medications for depression and mood stabilization may experience hair loss. Drugs that may cause this include: paroxetine hydrochloride (Paxil)
How quickly does Cymbalta start working?
Cymbalta (duloxetine) is an antidepressant. As with all antidepressants, some physical symptoms of depression may improve within a week or two of starting it. But it can take up to two months to see the full effect of Cymbalta on depression. When Cymbalta is used for pain, it generally improves within two weeks.
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