What Are The Worst Side Effects Of Cymbalta?

Tell your doctor right away if any of these serious side effects occur: confusion, easy bruising/bleeding, decreased interest in sex, changes in sexual ability, muscle cramps/weakness, shaking (tremor), difficulty urinating, signs of liver problems (such as nausea that doesn’t go away, stomach/abdominal pain, vomiting,

Why is Cymbalta so bad?

Serious Side Effects and Warnings
Cymbalta may cause enlarged liver and increased liver enzymes. A March 2021 case report of a 43-year-old woman who was admitted to the hospital for acute liver failure demonstrates that while drug induced liver injury (DILI) is rare, it has been linked to use of Cymbalta.

Is Cymbalta a high risk medication?

Cymbalta is a commonly prescribed Antidepressant used to treat generalized anxiety disorder and depression. Although generally considered nonaddictive, Cymbalta presents a high risk for abuse and dependence.

What is the best replacement for Cymbalta?

What is a good alternative to Cymbalta? Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SNRI). Other SNRIs include Effexor (venlafaxine), Pristiq (desvenlafaxine), and Savella (milnacipran).

What are the long term side effects of Cymbalta?

Side effects of Cymbalta include nausea, dry mouth, and constipation. Cymbalta is not addictive when taken properly, although withdrawal symptoms can occur. Long-term effects of Cymbalta may include appetite changes and weight gain.

Does Cymbalta change your personality?

Results to date suggest that duloxetine can produce adaptive changes in behavioural and neural mechanisms that characterise low mood, consistent with growing evidence that antidepressants can modulate emotion recognition and social functioning in clinical depression.

Who should not take Cymbalta?

You should not use this medicine if you have had an allergic reaction to duloxetine, or if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days. You should not use this medicine if you have uncontrolled narrow-angle glaucoma.

How do you know if Cymbalta is not working?

Signs that your antidepressant might not be working include:

1. You feel more or the same amount of sadness, anxiety, or irritability after several weeks or months of taking the medication.
2. You feel slightly better, but still feel that your depression is affecting your ability to function.
3. You are having trouble sleeping.

How much Cymbalta is fatal?

Fatal overdoses of duloxetine have been reported with as little as 1,000 milligrams. Overdoses generally manifest with sleepiness, coma, serotonin syndrome, seizures, tachycardia, hyper or hypotension, and vomiting. Treatment should be supportive.

Is Cymbalta worth taking?

Cymbalta (duloxetine) is good for treating depression, anxiety, and some forms of long-term pain, but it’s more likely than other antidepressants to cause problems if you drink alcohol or have high blood pressure.

Can Cymbalta cause joint pain?

Check with your doctor right away if you have blistering, peeling, or loosening of the skin, chills, cough, diarrhea, itching, joint or muscle pain, red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, or unusual tiredness or weakness

What is a natural substitute for Cymbalta?

Supplements such as SAMe, St. John’s Wort, 5-HTP, Vit D, magnesium, saffron, Omega-3 fatty acids, are some examples. Get tested for food allergies, nutritional and hormonal deficiencies, which have been shown to cause symptoms like those for which antidepressants are prescribed.

Which is better gabapentin or duloxetine?

This study concluded that there is no significant difference between duloxetine and gabapentin for treating PDPN and that the efficacies of the 2 drugs are equal. The study researchers recommended that clinicians organize management of patients with diabetes mellitus based on drug prices and the fewest side effects.

What’s better Lexapro or Cymbalta?

Is Cymbalta or Lexapro better? Cymbalta and Lexapro appear to be similarly effective in treating depression. Large meta-analyses of multiple studies indicate that the higher rate of adverse events with Cymbalta may be a reason to try Lexapro first in most patients.

Do Cymbalta side effects go away?

Some side effects may go away once the drug is stopped. However, other side effects, like liver failure, may not go away if you stop the drug. If you have questions about your risk for side effects with Cymbalta, talk with your doctor or pharmacist.

Does your brain go back to normal after antidepressants?

The process of healing the brain takes quite a bit longer than recovery from the acute symptoms. In fact, our best estimates are that it takes 6 to 9 months after you are no longer symptomatically depressed for your brain to entirely recover cognitive function and resilience.

How common are Cymbalta side effects?

The most commonly observed adverse reactions in CYMBALTA-treated patients in all the pooled adult populations (i.e., MDD, GAD, DPNP, FM, OA, and CLBP) (incidence of at least 5% and at least twice the incidence in placebo-treated patients) were nausea, dry mouth, somnolence, constipation, decreased appetite, and

Does Cymbalta make you lazy?

But even the newer classes of antidepressants—including selective serotonin reuptake inhibitors (SSRIs) such as Prozac (fluoxetine) and serotonin and norepinephrine reuptake inhibitors (SNRIs) such as Cymbalta (duloxetine)—can lay you low.

Can duloxetine cause heart problems?

Increased blood pressure and heart rate have been reported in duloxetine trials. The proposed mechanism for duloxetine-induced tachycardia is its effects on norepinephrine, which impact the cardiovascular system.

What is a brain zap?

Brain zaps are electrical shock sensations in the brain. They can happen in a person who is decreasing or stopping their use of certain medications, particularly antidepressants. Brain zaps are not harmful and will not damage the brain. However, they can be bothersome, disorienting, and disruptive to sleep.

Is Cymbalta hard on the kidneys?

Cymbalta should not damage your kidney function with Stage 3 chronic kidney disease (CKD). Your prescribing physician should take this into consideration.