How Does Lithium Work In Mania?

Glutamate is an excitatory neurotransmitter that is elevated during mania. Lithium acutely stimulates the NMDA receptor, increasing glutamate availability in the postsynaptic neuron. After chronic administration, lithium induces NMDA downregulation, this way lithium modulates glutamate neurotransmission. Does lithium reduce mania? … Continue reading

Does Seroquel Help Bpd?

A randomized, double-blind, placebo-controlled, study of the use of quetiapine fumarate in the treatment of adults with borderline personality disorder found a significant reduction in the severity of symptoms of compared with those receiving placebo. Is quetiapine good for BPD? … Continue reading