Some products that may interact with this drug include: certain antidepressants (such as amitriptyline, nortriptyline, phenelzine), certain antibiotics (carbapenems such as imipenem), irinotecan, mefloquine, orlistat, other medications for seizure (such as ethosuximide, lamotrigine, phenytoin, rufinamide, topiramate),
What is contraindicated with Depakote?
Depakote is contraindicated in patients with known hypersensitivity to the drug [see Warnings and Precautions (5.11)]. Depakote is contraindicated in patients with known urea cycle disorders [see Warnings and Precautions (5.5)]. Hepatic failure resulting in fatalities has occurred in patients receiving valproate.
What medications can you not take at the same time?
List of Drugs That Interact
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Antacids.
- Decongestants, such as dextromethorphan or pseudoephedrine.
- First-generation antihistamines.
- Certain foods.
- Herbal products and minerals.
- Histamine2 (H2)-receptor antagonists such as cimetidine and ranitidine.
Does Zoloft interact with Depakote?
Interactions between your drugs
Treatment with sertraline may occasionally cause blood sodium levels to get too low, a condition known as hyponatremia, and using it with divalproex sodium can increase that risk.
Does ibuprofen interfere with Depakote?
Interactions between your drugs
No interactions were found between Depakote and ibuprofen. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Can Depakote and Seroquel be taken together?
Interactions between your drugs
Using divalproex sodium together with QUEtiapine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.
What are signs of Depakote toxicity?
CNS findings in cases of VPA overdose may include the following:
- Coma.
- Confusion.
- Somnolence.
- Worsened seizure control.
- Dizziness.
- Hallucinations.
- Irritability.
- Headache.
What two drugs can you not mix?
5 Over-the-Counter Medicines You Should Never Take Together
- Dangerous duo: Tylenol and multi-symptom cold medicines.
- Dangerous duo: Any combo of ibuprofen, naproxen, and aspirin.
- Dangerous duo: Antihistamines and motion-sickness medications.
- Dangerous duo: Anti-diarrheal medicine and calcium supplements.
- Dangerous duo: St.
What are the 3 types of drug interactions?
Drug interactions can be categorised into 3 groups: Interactions of drugs with other drugs (drug-drug interactions), Drugs with food (drug-food interactions) Drug with disease condition (drug-disease interactions).
Can I take all my meds together?
There are several risks when taking multiple medicines. You may be more likely to have side effects. Because most medicines can have side effects, the more medicines you take, the more likely you will have side effects. Taking certain medicines can also increase the risk for falls.
Can you take Tylenol with Depakote?
No interactions were found between Depakote and Tylenol.
What is a good antidepressant for bipolar?
Three drugs are FDA-approved for the treatment of bipolar depression: quetiapine (Seroquel) by itself, olanzapine (Zyprexa) when used with fluoxetine (Prozac) (which also comes as a combination pill called Symbyax), and lurasidone (Latuda) used alone or with lithium or valproate (Depakote).
Can I take Xanax with Depakote?
ALPRAZolam divalproex sodium
Combining these medications may increase the risk of harmful effects to a fetus. It is important to tell your doctor about all other medications you use, including vitamins and herbs.
Is 500mg of Depakote a lot?
Depakote ER is indicated for prophylaxis of migraine headaches in adults. The recommended starting dose is 500 mg once daily for 1 week, thereafter increasing to 1000 mg once daily.
Can you drink alcohol on Depakote?
Alcohol can increase the nervous system side effects of divalproex sodium such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with divalproex sodium.
Does Depakote help you sleep?
Valproic acid (Depakote) – helps somewhat with insomnia.
What does Depakote do for bipolar?
The medication Depakote (divalproex sodium) is an anticonvulsant. Doctors prescribe it to treat seizure disorders and to prevent migraine headaches. People also use it to manage the manic phase of bipolar disorder. Depakote side effects can be serious and sometimes fatal.
Can Depakote and OLANZapine be taken together?
Using divalproex sodium together with OLANZapine can increase the risk of liver problems. Talk with your doctor before using these medications together. This can cause fever, rash, loss of appetite, nausea, vomiting, fatigue, right upper abdomianal pain, dark urine, and yellowish skin.
Is Depakote a psychotic drug?
Depakote is also used to treat epilepsy and migraine headaches. Abilify is also used to treat schizophrenia, depression, autistic disorder, and some irritable behavior disorders. Depakote and Abilify belong to different drug classes. Depakote is an anticonvulsant and Abilify is a psychotropic drug (antipsychotic).
What is the toxic level for Depakote?
Its action is similar to that of other common anticonvulsants, such as phenytoin and carbamazepine. The therapeutic range for valproic acid is 50-100 mcg/mL. The toxic level is >100 mcg/mL.
Is Depakote a good drug?
Depakote has an average rating of 6.2 out of 10 from a total of 292 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 29% reported a negative effect.