Rarely, Depakote and Depakote ER may cause hallucinations (seeing or hearing things that aren’t really there). Hallucinations were a rare side effect reported in clinical trials of Depakote DR tablets and Depakote ER tablets.
What are the most common side effects of Depakote?
A: Common side effects experienced with Depakote include drowsiness, nausea, abdominal pain, diarrhea, vomiting, low platelet count, tremors, tiredness, and hair loss. The side effects may be mild to moderate, but they may also be signs of a more serious condition.
What happens when Depakote levels are too high?
Symptoms of overdosage of Depakote include changes in consciousness, fainting, and slow or irregular heartbeat. Contact your doctor urgently if you experience stomach pain that spreads to your back, nausea and vomiting, dark urine, facial swelling, loss of appetite, or yellowing of the skin or eyes.
What are signs of Depakote toxicity?
CNS findings in cases of VPA overdose may include the following:
- Coma.
- Confusion.
- Somnolence.
- Worsened seizure control.
- Dizziness.
- Hallucinations.
- Irritability.
- Headache.
What drugs cause hallucinations?
People can experience hallucinations when they’re high on illegal drugs such as amphetamines, cocaine, LSD or ecstasy. They can also occur during withdrawal from alcohol or drugs if you suddenly stop taking them. Drug-induced hallucinations are usually visual, but they may affect other senses.
Does Depakote cause confusion?
confusion, tiredness, cold feeling, vomiting, change in your mental state; severe drowsiness; or. worsening seizures.
Can Depakote cause auditory hallucinations?
Rarely, Depakote and Depakote ER may cause hallucinations (seeing or hearing things that aren’t really there). Hallucinations were a rare side effect reported in clinical trials of Depakote DR tablets and Depakote ER tablets.
What is the toxic level for Depakote?
Its action is similar to that of other common anticonvulsants, such as phenytoin and carbamazepine. The therapeutic range for valproic acid is 50-100 mcg/mL. The toxic level is >100 mcg/mL.
Is 500mg of Depakote a lot?
Depakote ER is indicated for prophylaxis of migraine headaches in adults. The recommended starting dose is 500 mg once daily for 1 week, thereafter increasing to 1000 mg once daily.
What is a good level for Depakote?
Ordinarily, optimal clinical response is achieved at daily doses below 60 mg/kg/day. If satisfactory clinical response has not been achieved, plasma levels should be measured to determine whether or not they are in the usually accepted therapeutic range (50 to 100 mcg/mL).
Can Depakote cause vision problems?
SIDE EFFECTS: See also Warning section. Diarrhea, dizziness, drowsiness, hair loss, blurred/double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), unsteadiness, weight changes may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Can valproic acid cause hallucinations?
The exact mechanism of valproic acid-induced abnormal behavior is not known. However, valproic acid by increasing the level of brain Gama- amino-butyric acid (GABA) provokes dose related delirium, visual hallucinations and hyperactivity, particularly in children.
Can Depakote change your personality?
Divalproex sodium may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you notice any of these side effects, tell your doctor right away.
What medications can cause visual hallucinations?
A number of psychiatric medications such as olanzapine (Zyprexa), quetiapine (Seroquel), and haloperidol (Haldol) have all been associated with causing hallucinations, in addition to zolpidem (Ambien), eszopiclone (Lunesta), clonazepam (Klonopin), lorazepam (Ativan), ropinirole (Requip), and some seizure medications.
What triggers hallucinations?
There are many causes of hallucinations, including: Being drunk or high, or coming down from such drugs like marijuana, LSD, cocaine (including crack), PCP, amphetamines, heroin, ketamine, and alcohol. Delirium or dementia (visual hallucinations are most common)
Can certain medications cause hallucinations?
Kooky Hallucinations Triggered by Meds
Hallucinations can be seen, heard, felt, or even smelled. And while we usually associate hallucinations with recreational drugs like LSD, one well-known prescription drug that may also cause hallucinations is the sleep aid Lunesta (eszopiclone).
Does Depakote cause brain damage?
Divalproex treatment was associated with accelerated brain volume loss over 1 year and perhaps with greater cognitive impairment. The long-term clinical effects of these changes are not known.
How long does it take for Depakote side effects to go away?
Most common side effects, including nausea and tiredness, will improve after two to four months of taking Depakote.
How long does it take to get Depakote out of your system?
When taken by itself, the half-life of Depakote is roughly 14 hours, and it takes five half-lives to eliminate most drugs. So, while the levels of Depakote may not be high enough to have clinical effects, Depakote can remain in your system for about three days following a single dose.
What is a mild hallucination?
A mild form of hallucination is known as a disturbance, and can occur in most of the senses above. These may be things like seeing movement in peripheral vision, or hearing faint noises or voices. Auditory hallucinations are very common in schizophrenia.
What is reflex hallucination?
Reflex hallucinations are experienced under the influence of psychedelic drugs, wherein the patient perceives colorful visual hallucination in response to loud noises.
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