A 2007 study of epilepsy patients found that 44 percent of women and 24 percent of men gained 11 pounds or more while taking Depakote for about a year. The drug affects proteins involved in appetite and metabolism, although it’s not clear why it appears to affect women more than men.
What is the average weight gain on Depakote?
The average amount of weight gained during VPA treatment is approximately 6 kg (Biton, et al., 2001; Chengappa, et al., 2002) and women gain more weight compared with men (El-Khatib, et al., 2007). The mechanism by which VPA increases body weight is not understood.
Does everyone gain weight on Depakote?
Depakote often causes an increased appetite, which can lead to weight gain. People taking it to treat migraine headaches may have decreased serotonin levels, which can also lead to cravings and overeating. Depakote can also cause drowsiness, which may decrease activity level.
How do I keep from gaining weight on Depakote?
Here are some ways to lose weight gained due to medication use:
- Switch to a different medication. The first strategy to consider involves changing medications.
- Lower medication dosage.
- Limit portion sizes.
- Exercise.
- Eat more protein.
- Talk to a dietitian.
- Avoid alcohol.
- Get enough sleep.
Is there a bipolar medication that doesn’t cause weight gain?
You can’t control the side effects of medication, but you can talk to your doctor about switching to something else. They include: Lamotrigine (Lamictal, Lamictal XR, Lamictal ODT). This anticonvulsant isn’t linked to weight gain.
Does Rexulti cause weight gain?
Do not start or stop any medicines during treatment with REXULTI without first talking to your healthcare provider. The most common side effects of REXULTI include weight gain and restlessness or feeling like you need to move (akathisia).
Does everyone gain weight on olanzapine?
Olanzapine elicits the most weight gain of the SGAs. The Comparison of Atypicals for First Episode (CAFE) trial demonstrated that 80% of patients treated with olanzapine gained more than 7% of their initial body weight at week 52 (McEvoy et al., 2007).
Can you lose weight on bipolar meds?
Most bipolar drugs cause weight gain rather than weight loss. For example, several of them increase your blood sugar level, which can lead to weight gain. Others affect your energy level. During manic episodes, you typically may not sleep much and may burn off lots of energy.
Which antipsychotics cause the most weight gain?
The highest weight gain is with olanzapine, followed by clozapine, risperidone and aripiprazole, similar to adult patients. Differences in weight gain have been noted according to the diagnosis. Patients with autism treated with antipsychotics had greater weight gain.
How do you reverse weight gain from antipsychotics?
Jan. 8, 2008 — The diabetes drug metformin — especially with a diet/exercise regimen — largely reverses the weight-gain side effect of antipsychotic drugs.
How long does it take to lose weight after stopping olanzapine?
Weight was recorded at 3, 6, and 12 months. Results: Patients incurred an average weight loss of 2.7 +/- 0.7 kg (p = 0.001) after switching patients from olanzapine SOT to olanzapine ODT at 12 months. Peak weight loss was observed at 6 months; however, significant weight loss was achieved as early as 3 months.
What bipolar medication causes weight loss?
Topiramate led to substantial weight loss in patients with bipolar disorders in these studies. The efficacy of topiramate as an adjunct treatment in patients with mood disorders has been demonstrated.
Which antipsychotic has least weight gain?
Antipsychotics with a lower risk of weight gain are:
- Aripiprazole (Abilify)
- Asenapine (Saphris)
- Brexipiprazole (Rexulti)
- Haloperidol (Haldol)
- Lurasidone (Latuda)
- Ziprasidone (Geodon)
Is Topamax used for bipolar?
Topiramate is a medication that works in the brain and is sometimes used in patients with bipolar disorder (also known as manic depression). It is approved for the treatment of seizures (epilepsy) in adults and children in combination with other anticonvulsants and for preventing migraine headaches in adults.
What are the side effects of Depakote?
A: Common side effects experienced with Depakote include drowsiness, nausea, abdominal pain, diarrhea, vomiting, low platelet count, tremors, tiredness, and hair loss. The side effects may be mild to moderate, but they may also be signs of a more serious condition.
Can bipolar cause weight loss?
Bipolar depression often comes with significant weight fluctuation on its own, more than 5% loss or gain of body weight in one month. So, a person weighing 165lbs would gain or lose over 2lbs a week. Typical bipolar depression often comes with weight loss.
Does Rexulti make you hungry?
Although your results may vary, the atypical antipsychotic class is often associated with weight gain, possibly due to changes in metabolism, an increased appetite and less physical activity because of side effects like drowsiness or fatigue.
Does Rexulti fatigue go away?
It depends. Some side effects of Rexulti may be temporary and last a few days or weeks. Most mild side effects, such as headache and tremors (shaking you can’t control), should go away on their own.
Does Rexulti give you energy?
It helped with anxiety but not really for my depression. Began Rexulti and is started working within 2 days. I started at 0.5 mg and worked myself up to 2 mg/day. I have significantly increased energy and went from sleeping 8 hours to 6 hours a night.
Will I gain weight on 2.5 mg olanzapine?
This drug may also cause significant weight gain and a rise in your blood cholesterol (or triglyceride) levels, especially in teenagers. These effects, along with diabetes, may increase your risk for developing heart disease. Discuss the risks and benefits of treatment with your doctor.
Does clozapine cause weight gain?
Clozapine is the only second line treatment for schizophrenia. It however causes weight gain in 75% of patients, with a third experiencing more than 7% weight gain over 3 years.
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